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Flexeril (Cyclobenzaprine Hcl) Side Effects, Interactions, Warning

6.20.2017 | Rachel Bargeman

Cyclobenzaprine hydrochloride is a white, crystalline tricyclic amine salt with the empirical formula C20H21N•HCl and a molecular weight of.

FLEXERIL 5 mg N=464 FLEXERIL 10 mg N=249 Placebo N=469 Drowsiness 29% 38% 10% Dry Mouth 21% 32% 7% Fatigue 6% 6% 3% Headache 5% 5% 8%

Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants ) concomitantly with MAO inhibitor drugs. Concomitant use of monoamine oxidase (MAO) inhibitors or within 14 days after their discontinuation.

Digestive: Vomiting; anorexia ; diarrhea; gastrointestinal pain; gastritis ; thirst; flatulence ; edema of the tongue; abnormal liver function and rare reports of hepatitis, jaundice and cholestasis.

Serum alkalinization, to a pH of 7.45 to 7.55, using intravenous sodium bicarbonate and hyperventilation (as needed), should be instituted for patients with dysrhythmias and/or QRS widening.

Cyclobenzaprine Side Effects, Dosage, Uses & More

11.25.2017 | Rachel Bargeman

Cyclobenzaprine is an oral drug used to relieve muscle spasms. Learn about side effects, warnings, dosage, and more.

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.

Cyclobenzaprine shouldn’t be used in people younger than 15 years.

NOTE: Healthline isn't a healthcare provider.

Cyclobenzaprine Uses, Dosage & Side Effects

3.17.2017 | Victoria Miers

Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes cyclobenzaprine side effects, interactions and indications.

Get emergency medical help if you have any signs of an allergic reaction to cyclobenzaprine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Take the medicine at the same time each day.

You should not use cyclobenzaprine if you are allergic to it, or if you have:

Data sources include Micromedex (updated June 2nd, 2017), Cerner Multum (updated June 5th, 2017), Wolters Kluwer (updated June 6th, 2017) and others. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.


12.26.2017 | Rachel Bargeman

Cyclobenzaprine, sold under the brand name Flexeril among others, is a muscle relaxer medication used to relieve skeletal muscle spasms and associated pain.

Cyclobenzaprine is regulated in the U.S. for prescription use only. Though it does not fall within most governmental guidelines as a controlled substance, possession of it without a valid or current prescription may be illegal, depending upon various state and local laws.

After sustaining an injury, painful muscle spasms may occur to stabilize the affected body part and prevent further damage. Cyclobenzaprine is used to treat such muscle spasms associated with acute, painful musculoskeletal conditions.


9.23.2017 | Logan Kirk

Cyclobenzaprine (Flexeril, Amrix, Fexmid) is a prescription muscle relaxant used to treat short-term relief of muscle spasms. Common side.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

MedicineNet does not provide medical advice, diagnosis or treatment. See additional information.

Take this quiz for answers about what is going on inside your body and brain that causes you to feel pain.

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996.